Vaccine hesitancy is listed as one of the top 10 global health threats by the WHO.Existing Ball - Catcher - Kits studies investigating the relationship between vaccine hesitancy and social media have found that misinformation and vaccine concerns on social media can cause significant declines in vaccine coverage rates.The objective of this study wa
Supervision and feedback for junior medical staff in Australian emergency departments: findings from the emergency medicine capacity assessment study
Abstract Background Clinical supervision and feedback are important for the development of competency in junior doctors.This study aimed to determine the adequacy of supervision of junior medical staff in Australian emergency departments (EDs) and perceived feedback provided.Methods Semi-structured telephone surveys sought quantitative and qualitat
Targeting IGF1/IGF1r signaling relieve pain and autophagic dysfunction in NTG-induced chronic migraine model of mice
Abstract Background Chronic migraine is a severe and common neurological disorder, yet its precise physiological mechanisms remain unclear.The IGF1/IGF1r signaling pathway plays a crucial role in pain modulation.Studies have shown that IGF1, by binding to its receptor IGF1r, activates a series of downstream signaling cascades involved in neuronal s
Identification and Characterization of (3Z):(2E)-Hexenal Isomerases from Cucumber
E-2-hexenal is a volatile compound that is commonly emitted by wounded or stressed plants.It belongs to the group of so-called green leaf volatiles (GLVs), which play an important role in transferring information to plants and insects.While most biosynthetic enzymes upstream of E-2-hexenal have been studied extensively, much less is known about the